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“More research is required into long-term topical corticosteroid use and its discontinuation, including topical steroid withdrawal, particularly in the pediatric population”… writes Dr. Belinda Sheary (Australia) who recently published an article describing “[a] qualitative case series [that] studied 10 children whose parents stopped their chronic topical corticosteroid use and subsequently developed features typically reported in adults experiencing topical steroid withdrawal.”

https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3144

And…

Also this, month the Journal of the Dermatology Nurses’ Association featured a case of Topical Steroid Withdrawal in their regular column: Teledermatology Viewpoint. “Although the exact mechanism of TSW has not yet been elucidated, some experts suggest that prolonged application of topical corticosteroids interferes with the production of nitric oxide, a potent vasodilator, in the endothelium (^{Rapaport & Lebwohl, 2003}) … On the other hand, an alternative explanation of symptoms of TSW is that prolonged topical steroid application may inhibit cortisol production by keratinocytes, which may weaken the barrier function of the skin as well as result in hypersensitivity (^{Fukaya, 2016}).”

https://journals.lww.com/jdnaonline/Fulltext/2019/03000/Burning_Red_Face.8.aspx