Acrylates

Allergic contact dermatitis is a T-cell dependent, delayed-type (Type IV) hypersensitivity reaction that has a high impact both in terms of patient morbidity and economics. This type of hypersensitivity reaction is primarily instigated by small lipophilic chemicals (haptens) with a molecular weight less than 500 Daltons. These chemical allergens trigger a complex immunologic cascade in the skin, which leads to the clinical picture of ACD.

” … generally, the resin poses little risk for initiating allergic reactions.The dental fillings and artificial nails that do cause reactions, however, do so because they are thought to still contain the sensitizing monomer MMA.”

“Of note, there are no acrylate formulations on the FDA-indicated commercially available patch tests (T.R.U.E. or Hermal).”

Citation: Jacob, S & Breithaupt, B.  July 2008. Focus on Acrylics. Skin & Aging. pp 28-32.