Balsam of Peru Diet

Balsam of Peru is a naturally occurring sticky substance that is harvested by wounding the Myroxylon pereirae tree, found in Central America. It has an odor similar to cinnamon and vanilla.  Notably, it cross-reacts with a number of synthetic fragrances found in perfumes, lotions, cleaning products, etc. It is a natural substance containing hundreds of components that also cross react with both natural and synthetic food flavorings.

In a significant number of people (but not all), who are confirmed on patch testing to be allergic to BOP, avoidance of skin contact with fragrances will lead to resolution of their allergic contact dermatitis (rash).  For a smaller subset of people (those more sensitized), avoiding fragrances is not enough. In these people, ingesting (eating/drinking) of foods high in BOP can trigger a widespread rash.

The standard patch test screening kit screens for the whole balsam of Peru extract.  In those with widespread rashes who have significant improvement on the low balsam diet, identification of the subgroup may be beneficial.  A diary of associated food flares can help identify the sub-unit food groups.  When available, a more extended patch test may be able to detect the individual component allergies, specifically benzoates, vanillin, ferrulic acid, cinnamates, and coniferins.

Because the complete low balsam of Peru diet can be a challenge to follow, identifying trigger foods within the sub-unit groups can simplify the avoidance diet, making it easier to follow.

High Risk Processed Foods

Foods that frequently contain ingredients high in BOP

Poultry, Meat, Fish, Seafood Possible BOP Ingredients
barbequed meats (pork, chicken, beef) paprika, cinnamon
canned meats and fish benzoates
fish and seafood, seasoned dill, paprika, cinnamon, allspice
frankfurter nutmeg, mace
ham, glazed cloves, cinnamon, vanilla
Fruits and Vegetables Possible BOP Ingredients
applesauce allspice, cinnamon
canned fruits and vegetables benzoates
fresh thin-skinned fruits and vegetables (apples, cucumbers) beeswax glaze (used to increase shelf life)
pickled vegetables dill, cloves
spiced fruits cloves, cinnamon, vanilla, allspice, nutmeg
Pastries and Other Desserts Possible BOP Ingredients
cakes, muffins, and cookies vanilla, cinnamon, nutmeg, cloves, allspice
candy vanilla, cinnamon, nutmeg, cloves, allspice
caramel vanilla
chocolate vanilla
custard and pudding vanilla
Danish pastries vanilla, cinnamon, nutmeg, cloves, allspice
ice-cream vanilla
spiced fruit pies vanilla, cinnamon, nutmeg, cloves, allspice
yogurt vanilla
Cuisines Possible BOP Ingredients
African cloves
Indian cloves, bay leaves, cinnamon, cloves
Italian tomato, basil, bay leaves
Mediterranean tomato, basil, dill
Mexican tomato, allspice
Middle Eastern cloves, allspice
Southeast Asian (Thai, Vietnamese) basil
Caribbean allspice, cinnamon, paprika, cloves
Condiments and Sauces Possible BOP Ingredients
barbeque sauce tomato, paprika, cinnamon, cloves
chutney citrus peel
ketchup tomato
maple syrup vanilla
marinades cloves, dill
marmalade and fruit jam citrus peel
pesto basil
pickles dill, cloves
salad dressings wine vinegars, dill
steak sauce tomato, cinnamon, cloves
Spice Blends Possible BOP Ingredients
Blackening seasoning paprika
Chili powder paprika
Chinese Five spice anise, cloves, cinnamon
Curry cloves, cinnamon
Dry rub paprika, cinnamon
Garam Masala cinnamon
Herbs de provence citrus zest, bay leaves
Jerk seasoning allspice, cinnamon
Pickling Spice dill, bay leaves
Pumpkin Pie Spice cinnamon, nutmeg, cloves
Quatre Epices/French Four Spice cloves, nutmeg
Beverages Possible BOP Ingredients
aperitifs (vermouth, lillet, pernod) citrus peel, anise, cloves, cinnamon, basil, vanilla
brandies citrus peel
citrus juices citrus peel
cola cinnamon, nutmeg, vanilla
spiced liquors (rum, bourbon, whiskey) anise, cloves, cinnamon, vanilla
spiced teas cinnamon, cloves, citrus peel, lemon balm

High Risk Primary Ingredients

Specific BOP avoidance diets

Avoid These Spices
allspice
anise
basil
bay leaves
cardamom
cassia (Chinese cinnamon, coumarin)
cinnamon
citrus peel
cloves
dill
Jamaican pepper
lemon balm
nutmeg and mace
paprika
synthetic vanilla
vanilla
Avoid These Fruits and Vegetables
asparagus
beets
blueberry
cranberry
huckleberry
tomato
Avoid These Beverages
beer
citrus juices
wine
Avoid These Grains
wheat and rye
Other Sources
beeswax
benzoate preservatives
brewer’s yeast
Avoid These Spices
cloves
synthetic vanilla
vanilla
Avoid These Beverages
beer
wine
Avoid These Grains
wheat
rye
Avoid These Spices
citrus peel
dill
Avoid These Fruits and Vegetables
tomato
Avoid These Beverages
wine
Avoid These Grains
wheat
rye
Avoid These Spices
anise
cassia (Chinese cinnamon, coumarin)
chocolate
cinnamon
vanilla
Avoid These Fruits and Vegetables
blueberry
cranberry
huckleberry
Avoid These Other Common Sources
brewer’s yeast
benzoate preservatives
Avoid These Spices
allspice
anise
basil
bay leaves
chocolate
cinnamon
cloves
dill
lemon balm
nutmeg and mace
synthetic vanilla
Avoid These Fruits and Vegetables
tomato
Avoid These Beverages
beer
Avoid These Fruits and Vegetables
asparagus
beets
tomato
Avoid These Beverages
beer
wine
Avoid These Other Common Sources
brewer’s yeast
Avoid These Spices
anise
basil
bay leaves
cassia (Chinese cinnamon, coumarin)
cinnamon
citrus peel
Avoid These Fruits and Vegetables
tomato
Avoid These Beverages
beer
citrus juice
wine

References

  1. Scheman A, Rakowski EM, Chou V, Chhatriwala A, Ross J, Jacob SE. Balsam of Peru: past and future. Dermatitis. 2013 Jul-Aug;24(4):153-60. doi: 10.1097/DER.0b013e31828afab2. Review. PubMed PMID: 23857009.
  2. Salam TN, Fowler JF Jr. Balsam-related systemic contact dermatitis. J Am Acad Dermatol. 2001 Sep;45(3):377-81. PubMed PMID: 11511833.
  3. Veien NK, Hattel T, Laurberg G. Can oral challenge with balsam of Peru predict possible benefit from a low-balsam diet? Am J Contact Dermat. 1996 Jun;7(2):84-7. PubMed PMID: 8796747.
  4. Balsam of Peru. [Internet PDF]. TRUE TEST Allergen Info Sheets. c2014 [cited April 14, 2016]. Available from https://www.smartpractice.com/dermatologyallergy/pdfs/allergens/Balsam-of-Peru-Patient-Info.pdf
  5. Balsam of Peru allergy [Internet]. New Zealand. Jan 10, 2016 [cited Apr 14, 2016]. Available from http://www.dermnetnz.org/dermatitis/balsam-of-peru-allergy.html
  6. Han E. 25 Spice Mixes from Around the World [Internet]. May 14, 2013 [cited April 14, 2016]. Available from http://www.thekitchn.com/spice-mixes-189368
  7. Cajun and Blackening Seasoning [Internet]. Epicurious. In the kitchen with the Pike Place Fish Guys. c2013 [cited April 14, 2016] Available from http://www.epicurious.com/recipes/food/views/cajun-and-blackening-seasoning-51168200
  8. Nelson, J. Spirits: The Art of the Aperitif [Internet]. Food & Wine. May 2002. [Cited April 14, 2016] Available from http://www.foodandwine.com/articles/spirits-the-art-of-the-aperitif
  9. How to Make Vermouth [Internet]. The Art of Drink. February 19, 2011 [cited April 14, 2016]. Available from https://www.artofdrink.com/ingredient/how-to-make-vermouth
  10. Ehrlich, SD, NMD. Lemon Balm. [Internet]. Complementary and Alternative Medicine Guide. University of Maryland Medical Center. Jan 2, 2015 [cited April 17, 2016]. Available from http://umm.edu/health/medical/altmed/herb/lemon-balm