Nickel Allergic Contact Dermatitis

(Ni-ACD)

Allergic contact dermatitis is a T-cell dependent, delayed-type (Type IV) hypersensitivity reaction that has a high impact both in terms of patient morbidity and economics. This type of hypersensitivity reaction is primarily instigated by small lipophilic chemicals (haptens) with a molecular weight less than 500 Daltons. These chemical allergens trigger a complex immunologic cascade in the skin, which leads to the clinical picture of nickel allergic contact dermatitis.

Living with Nickel Allergy

Goblin’s Copper

Learn the history behind Ni-ACD.

Common Products

Click for a list of common products with nickel!

Nickel Free?

Learn how to check for nickel in your products!

Low Nickel Diet

Learn how to avoid systemic Ni-ACD with diet.